Hemodynamic Responses to Rapid Saline Loading

Hemodynamic responses to rapid saline loading: the impact of age, sex, and heart failure.

BACKGROUND Hemodynamic assessment after volume challenge has been proposed as a way to identify heart failure with preserved ejection fraction. However, the normal hemodynamic response to a volume challenge and how age and sex affect this relationship remain unknown. METHODS AND RESULTS Sixty healthy subjects underwent right heart catheterization to measure age- and sex-related normative resp...

Effects of saline loading on the renin, erythropoietin, and blood pressure responses to canine renal allotransplantation.

Hemodynamic Responses

Angiotensin II (Ang II) and atrial natriuretic factor (ANF) appear to act as functional antagonists in the regulation of fluid and electrolyte homeostasis and blood pressure. To further define the relations between these hormones in vivo, we investigated the effect of low doses ofAng II (1-10 ng/kg/min) on plasma ANF levels. We also evaluated the influence ofANF release on the renal and hormona...

Hemodynamic and metabolic responses to neuronal inhibition.

Functional magnetic resonance imaging (fMRI) was used to investigate the changes in blood oxygenation level dependent (BOLD) signal, cerebral blood flow (CBF) and cerebral metabolic rate of oxygen consumption (CMR(O(2))) accompanying neuronal inhibition. Eight healthy volunteers performed a periodic right-hand pinch grip every second using 5% of their maximum voluntary contraction (MVC), a para...

Brain microvascular hemodynamic responses to induced seizures.

Arteriolar diameters and venular erythrocyte velocities in the small pial vessels on the surface of the cat brain were measured by TV methods during induced epileptic seizures through a cranial window. Grand mal seizures maximally dilated arterioles and increased venular erythrocyte velocity up to 400%. High positive correlation existed between changes in CSF hydrogen ion concentration and pial...